Drive the very popular U.S. Highway 441 through Great Smoky Mountains National Park from Cherokee. First stop should be the Oconaluftee Visitor Center and Mountain Farm Museum. Then drive 18 miles and climb 3,000 ft. to Newfound Gap on the Tennessee border. Many turn around here or drive up to Clingmans Dome. Another option is a hike on the Appalachian Trail.
Newfound Gap Road